HPLC detectorsalways have a bandwidth of 5-8nm
Yes, when it comes to the HPLC detectors, they always have a bandwidth of 5-8nm, which means that they can only work effectively between the wavelength of 190-700nm when dealing with UV absorbance. In the context of active ingredients monitoring, sensitivity is one of the critical requirements, and it is always influenced by baseline noise. Further, the notion of dual-wavelength recognition features is significant for the concurrent monitoring of the active ingredients and preservatives in drug products is mandatory. Therefore, a UV wavelength of 190nm falls between the speculated ranges of the wavelength that is effective for monitoring of the active ingredients that is applied in the procedure above.
Apart from paracetamol, another analgesic agent that could be used in this process is salicylates such as floctafenine, flurbiprofen, diflunisal, etc., which are non-steroidal anti-inflammatory drugs. This another remarkable analgesic agent that could be applied in this process, given that they always work effectively in determining the pharmaceutical products in the water sample. This agent works by constraining the actions of cyclooxygenase (COX) enzymes. In this case, even though Asprin is salicylates, it is not what is being referred to in this case since it only represents acetylsalicylic acid. On the other hand, what this discussion implies is the acids that contain salicylates such as the calcium and sodium salicylates. Overall, another alternative that could be deployed in this procedure is salicylates, such as floctafenine, flurbiprofen, diflunisal, etc.